IPSS

IPSS may refer to:

Medicine

 * Inferior petrosal sinus sampling, a procedure to help distinguish types of Cushing's disease
 * International Prognostic Scoring System, an evaluation method to determine the severity of myelodysplastic syndrome
 * International Prostate Symptom Score, a short questionnaire to help screen for benign prostatic hyperplasia (BPH)

Other

 * Infrasonic passive seismic spectroscopy, a geological exploration and monitoring technique
 * International Packet Switched Service, a telecommunications data transmission protocol
 * Institute for Peace and Security Studies, a university in Ethiopia