ISSE

Isse or ISSE may refer to:

Places

 * Isse, village and commune in north-eastern France
 * Issé, village and commune in north-western France

Computing

 * Information Systems Security Engineering
 * Internet Streaming SIMD Extensions, an SIMD instruction set extension to the x86 architecture by Intel introduced in 1999
 * Integer Streaming SIMD Extensions, an informal name for MMX extensions associated with 3DNow! extensions

Other uses

 * Issé (opera), by André Cardinal Destouches
 * International Secondary School Eindhoven, a school in the Netherlands
 * International Students for Social Equality
 * Hirsi Magan Isse (1935–2008), scholar and a leading figure of the Somali Revolution