ISTC

ISTC may refer to:


 * Illinois Sustainable Technology Center housed at the Prairie Research Institute
 * Incunabula Short Title Catalogue
 * Independent Sector Treatment Centre, part of the UK National Health Service
 * Institute of Scientific and Technical Communicators
 * International Science and Technology Center
 * International Space Training Center, the fictional institution behind Mission: Space ride at Epcot
 * International Standard Text Code, a numeric code in development by the ISO for textual works
 * International Student Travel Confederation
 * The former Iron and Steel Trades Confederation trade union, now part of Community (trade union)