Inositol-1,4-bisphosphate 1-phosphatase

The enzyme inositol-1,4-bisphosphate 1-phosphatase (EC 3.1.3.57) catalyzes the reaction


 * 1 D -myo-inositol 1,4-bisphosphate + H2O $$\rightleftharpoons$$ 1 D -myo-inositol 4-phosphate + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is  D -myo-inositol-1,4-bisphosphate 1-phosphohydrolase. This enzyme is also called inositol-polyphosphate 1-phosphatase. This enzyme participates in inositol phosphate metabolism and phosphatidylinositol signaling system.

Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and.