Integrin alpha 10

Integrin alpha-10 also known as ITGA10 is a protein that in humans is encoded by the ITGA10 gene.

Function
Integrins are integral membrane proteins composed of an alpha chain and a beta chain, and are known to participate in cell adhesion as well as cell-surface mediated signalling. The I-domain containing alpha 10 combines with the integrin beta 1 chain (ITGB1) to form a novel collagen type II-binding integrin expressed in cartilage tissue.

Related gene problems

 * TAR syndrome
 * 1q21.1 deletion syndrome
 * 1q21.1 duplication syndrome