Irion

Irion is a surname. Notable people with the surname include:


 * Alfred Briggs Irion (1833–1903), U.S. Representative from Louisiana
 * Johnny Irion (born 1969) and Sarah Lee Guthrie (born 1979), United States musical duo
 * Robert Anderson Irion (1804–1861), physician, surveyor and Secretary of State of Texas
 * Naomi Irion (died 2022), American murder victim