Isaac Johnson

Isaac Johnson may refer to:


 * Isaac Johnson (politician) (1803–1853), governor of Louisiana
 * Isaac Johnson (colonist) (1601–1630), English clergyman and one of the Puritan founders of Massachusetts
 * Isaac Johnson (cricketer) (1808–1874), English cricketer
 * Isaac Johnson (racing driver) (born 2000), American racing driver
 * Isaac Charles Johnson (1811–1911), British cement manufacturer