Isabella of Spain

Isabella of Spain or Isabel of Spain may refer to:


 * Isabella I of Castile (1451–1504), queen
 * Isabella II of Spain (1830–1904), queen
 * Isabella of Austria (1501–1526)
 * Infanta Isabella Clara Eugenia of Spain (1566–1633), archduchess of the Netherlands
 * María Isabella of Spain (1789–1848)
 * Isabella, Princess of Asturias (1851–1931)