Isom

Isom may refer to:

Places

 * Isom, Kentucky, an unincorporated community in Letcher County
 * Isom, Virginia, an unincorporated community in Dickenson County
 * Isom, West Virginia, an unincorporated community in Logan County
 * Lake Isom, a lake in Lake County, Tennessee

People

 * Isom (surname)
 * Isom Dart (1849-1900), American rodeo clown and stunt rider, rancher, and horse and cattle rustler

Other

 * Isom, a comic book by Cliff Richards and Eric July
 * ISO base media file format
 * USS William Isom (ID-1555), a United States Navy tanker