Isotta

Isotta may refer to:


 * the Italian form of the name Iseult
 * Isotta Nogarola (1418–1466), Italian writer and humanist
 * Isotta degli Atti (died 1474), an Italian regent
 * Isotta Brembati (died 1586), Italian poet and countess
 * Isotta Gervasi (1889–1967), Italian medical doctor
 * Isotta Brothers (19th century), Italian hoteliers
 * Paolo Isotta (1950–2021), Italian musicologist
 * Isotta Fraschini, Italian luxury car manufacturer