JTB

JTB may refer to:


 * Jets to Brazil, an American rock band
 * John the Baptist (died circa 30), Jewish preacher and ascetic
 * JTB (gene), a human gene
 * Journal of Theoretical Biology, a scientific journal
 * JTB Corporation, formerly Japan Travel Bureau, the largest travel agency in Japan
 * Justified true belief, a philosophical definition of knowledge
 * JTB (software), a preprocessor that produces JavaCC files
 * Joint IED Defeat (JIEDD) Test Board, an organization within the Joint Improvised Explosive Device Defeat Organization
 * J. Turner Butler Boulevard, a major expressway in Jacksonville, Florida carrying the designation Florida State Road 202