James Byrnes

James Byrnes may refer to:


 * James Byrnes (Australian politician) (1806–1886), New South Wales politician
 * James Byrnes (sailor) (1838–1882), Irish sailor and Medal of Honor recipient
 * James F. Byrnes (1882–1972), American politician and Supreme Court Justice from South Carolina
 * Jim Byrnes (baseball) (1880–1941), American baseball player
 * Jim Byrnes (actor) (born 1948), American actor and blues musician
 * Jim Byrnes (producer), American television producer and writer.