James Clayton

James or Jim Clayton may refer to:


 * James Clayton (priest) (died 1588), English Roman Catholic priest
 * James Clayton (engineer) (1870s–1946), British railway locomotive engineer
 * Gordon Clayton (footballer, born 1910) (James Gordon Thomas Clayton), English footballer
 * Jim Clayton (rower) (1911–1992), New Zealand rower
 * Jim Clayton (businessman) (born 1934), American entrepreneur who founded Clayton Homes
 * Jim Clayton (musician) (born 1967), Canadian jazz musician
 * James Clayton (baritone), Australian baritone, see 12th Helpmann Awards
 * Clayton Chitty, aka Clayton James, Canadian actor and model