James Duane (disambiguation)

James Duane (1733–1797) was a member of the Continental Congress and mayor of New York City.

James Duane may also refer to:
 * James Duane (fireboat), a fireboat of New York City named after the mayor
 * James Duane (professor) (born 1959), American lawyer
 * James Chatham Duane (1824–1897), engineering officer in the Union Army during the American Civil War