James Mahoney

James Mahoney may refer to:


 * James Mahony (1810–1879), Irish artist and engraver
 * James Mahoney (politician) (1873–1938), British priest and politician
 * James Mahoney (pulmonologist) (1958–2020), American pulmonologist and internist
 * James Patrick Mahoney (New York bishop) (1925–2002), American bishop
 * James Patrick Mahoney (1927–1995), Canadian bishop
 * James E. Mahoney (1858–1926), United States Marine Corps officer