James O'Neill

James or Jimmy O'Neill may refer to:


 * James O'Neill (actor, born 1847) (1847–1920), father of the playwright Eugene O'Neill
 * James O'Neill (actor, born 1863) (1863–1938), vaudeville and early film actor
 * James E. O'Neill (1929–1987), American acting Archivist for the National Archives
 * James O'Neill (baseball) (died 1993), winner of College World Series Most Outstanding Player award in 1952
 * James O'Neill (New Zealand politician) (1819–1882)
 * James O'Neill (Washington politician) (1824–1913), American politician in Oregon and Washington states
 * James O'Neill (priest) (died 1922), founder of the Knights of Saint Columbanus
 * James O'Neill (jurist) (1847–1929), American jurist and politician
 * James O'Neill (Wisconsin settler) (1810–1882), American settler, politician, and sawmill owner
 * James Ryan O'Neill (born 1947), Australian serial killer
 * Jimmy O'Neill (footballer, born 1931) (1931–2007), Irish international footballer
 * James P. O'Neill (born 1950s), New York City police commissioner
 * James R. O'Neill (1833–1863), American Civil War artist and correspondent
 * Jamie O'Neill (born 1962), Irish author
 * Tip O'Neill (baseball) (1860–1915), Canadian Baseball Hall of Fame inductee
 * James Hugh O'Neill (1892–1972), American Catholic priest
 * James E. O'Neill Jr. (1929–2002), Michigan politician