James O'Toole

James O'Toole may refer to:


 * James O'Toole (business figure), pioneer of the internet and internet marketing in Australia,
 * James O'Toole (American politician) (born 1958), politician in the Missouri House of Representatives
 * James O'Toole (reporter), American journalist
 * James O'Toole (mobster) (1929–1973), Irish-American criminal
 * James O'Toole (Irish politician) (died 1969), Irish Fianna Fáil politician