James Sexton (disambiguation)

Sir James Sexton (1856–1938) was British trade union leader and politician.

James Sexton may also refer to:
 * James A. Sexton (1844–1899), American soldier, businessman and politician
 * James Sexton (attorney) (born 1972), American family law attorney
 * Buck Sexton (James Buckman Sexton, born 1981), American radio and television talk show host, author and conservative political commentator