James Shapiro

James Shapiro may refer to:


 * Jim Shapiro (attorney), American attorney
 * Jim Shapiro (drummer) (born 1965), American rock musician
 * James Shapiro (physician), British-born Canadian doctor who developed the Edmonton protocol
 * James A. Shapiro (born 1943), American professor of biochemistry and molecular biology
 * James S. Shapiro (born 1955), American professor of English and comparative literature, non-fiction author