James W. and Anne Smith Phyfe Estate

James W. and Anne Smith Phyfe Estate is a national historic district located at Nissequogue in Suffolk County, New York. The district encompasses an estate with two contributing buildings. The estate house is a large two-story Neoclassical style structure built in 1904. It features a colossal attic pediment carried on two-story Ionic order columns enclosing a cantilevered balcony on the second floor. Located nearby is a contributing carriage house.

It was added to the National Register of Historic Places in 1993.