Jan Sapieha

Jan Sapieha may refer to:
 * Iwan Semenowicz Sapieha or Jan Sapieha (c. 1431-1517), progenitor of the Kodeń line of the Sapieha family
 * Jan Piotr Sapieha (1569–1611), Polish-Lithuanian nobleman, father of Paweł Jan Sapieha
 * Jan Stanisław Sapieha (1589–1635), Chancellor of Lithuania, 1621–1635
 * Jan Kazimierz Sapieha the Younger (1637–1720/1642–1720), Duke from 1700, voivode of Wilno, from 1682 Grand Hetman of Lithuania
 * Jan Kazimierz Sapieha the Elder (died 1730), Grand Hetman of Lithuania
 * Jan Fryderyk Sapieha (1680–1751), Grand Recorder of Lithuania, 1706–1709; from 1716 castellan of Troki; from 1735 Grand Chancellor of Lithuania