John Cairns

John Cairns may refer to:


 * John Cairns (biochemist) (1922–2018), biochemist who first demonstrated the structure and replication of the E. coli genome
 * John Cairns (cricketer) (1925–2014), English cricketer
 * John Cairns (politician) (1859–1923), British politician, MP for Morpeth
 * John Cairns (1818–1892), Scottish divine and writer
 * John Cairns (1857–1922), United Presbyterian Church minister, writer and biographer
 * John Cairns (born 1942), former moderator of the general assembly of the Church of Scotland
 * John Cairns (footballer) (1902–1965), Scottish football forward