John E. Smith (disambiguation)

John E. Smith was a Swiss immigrant to the United States who served as a Union general during the American Civil War.

John E. Smith may also refer to:


 * John E. Smith (New York politician) (1843–1907), American politician
 * John E. Smith, Director of U.S. Treasury Office of Foreign Assets Control
 * John Eldon Smith (1930–1983), American murderer
 * John Eldrid Smith, South African judge
 * John Edwin Smith, American philosopher
 * J. E. Smith (c. 1862/1863–1912), English trade union leader