José Acosta

José Acosta may refer to:
 * José Acosta (baseball) (1891–1977), Cuban baseball player
 * José Acosta Cubero (born 1947), Spanish politician
 * José de Acosta (1540–1600), Jesuit naturalist and missionary in Latin America
 * José Eugenio Acosta (1942–2006), Argentine equestrian
 * José Gerónimo Lluberas Acosta (1956–2003), Puerto Rican physician
 * José Julián Acosta (1825–1891), journalist and advocate of the abolition of slavery in Puerto Rico