José Luis Rodríguez

José Luis Rodríguez may refer to:


 * José Luis Rodríguez Vélez (1915–1984), Panamanian musician
 * José Luis Rodríguez (singer) (born 1943), El Puma, Venezuelan singer and actor
 * José Luis Rodríguez Zapatero (born 1960), former Prime Minister of Spain (2004–2011)
 * José Luis Rodríguez (footballer, born 1963), El Puma, former Argentine football striker
 * José Luis Loreto (José Luis Rodríguez Loreto, born 1971), former Spanish football striker
 * José Luis Rodríguez Pittí (born 1971), Panamanian writer, documentary photographer, and computer systems engineer
 * José Luis Rodríguez Aguilar (born 1994), Chilean cyclist
 * José Luis Rodríguez (footballer, born 1997), Uruguayan footballer
 * José Luis Rodríguez (footballer, born 1998), Panamanian footballer
 * José Luis Rodríguez Jiménez (born 1961), Spanish historian