José Machado

 José Machado may refer to:


 * José Machado (rower) (born 1928), Portuguese Olympic rower
 * José Ramón Machado Ventura (born 1930), vice-president of Cuba (2008 to date)
 * José Machado (São Tomé and Príncipe), Portuguese governor of São Tomé and Príncipe (1955–56)
 * José Manuel Machado (1756–1852), Spanish soldier, ranchero, early citizen of the pueblo of San Diego