José Serrano

José Serrano may refer to:
 * José António Serrano (1851–1904), Portuguese physician and anatomist
 * José E. Serrano (born 1943), Member of the U.S. House of Representatives for a portion of The Bronx, New York
 * José M. Serrano (born 1972), his son, New York State Senator
 * José Serrano (Ecuadorian politician) (born 1970), Ecuadorian political figure, currently Minister of the Interior
 * José Serrano (composer) (1873–1941), Spanish zarzuela composer
 * José María Galante Serrano (1948–2020), Spanish activist known as Chato Galante
 * José Mariano Serrano (1788–1852), Bolivian member of the Congress of Tucumán
 * José Serrano (footballer, born 1981), Spanish footballer
 * Rosso José Serrano (born 1942), Colombian police officer
 * José Serrano (footballer, born 2002), Venezuelan footballer