Juan Santiago

Juan Santiago can refer to:
 * Juan Santiago, Dominican Republic, a municipality in the Elías Piña Province
 * Juan Santiago (boxer), an American professional welterweight boxer
 * Juan Santiago Gordón, a Chilean hurdler
 * Juan Carlos Santiago, a former Spanish basketball player
 * Juan Santiago, a character on General Hospital
 * Juan Santiago (footballer), an Uruguayan footballer who played in the 1945 South American Championship
 * Juan G. Santiago, American engineer