KNT-127

KNT-127 is an opioid drug selective for the delta opioid receptors. It might be used as an analgesic and anxiolytic.

Potential uses
KNT-127 can be used as an analgesic. In mice, it was able to reverse inflammatory hyperalgesia.

Multiple tests have shown KNT-127 to be able to reduce anxiety, in a similar way to muscimol, a GABAA agonist.

Tolerance
Chronic administration of KNT-127 created cross-tolerance to the analgesic effects of SNC-80, another opioid.