Karen Lewis (disambiguation)

Karen Lewis was an American labor leader who served as president of the Chicago Teachers Union from 2010 to 2014.

Karen Lewis may also refer to:
 * Karen Lewis (screenwriter) (born 1950s), American television soap opera writer
 * Karen Lewis Young (born 1951), member of the Maryland House of Delegates since 2015
 * Karen Lewis, actress and spouse of Michael Attenborough