Karl Friedrich

Karl Friedrich may refer to:


 * Karl Friedrich, Grand Duke of Baden (1728–1811)
 * Karl Friedrich, Duke of Holstein-Gottorp (1700–1739)
 * Karl Friedrich, Duke of Saxe-Meiningen (1712–1743)
 * Karl Friedrich, Prince of Hohenzollern (born 1952)
 * Karl Friedrich (tenor) (1905–1981)
 * Karl Friedrich, Prince of Hohenzollern-Sigmaringen (1724–1785)