Karls

Karls may refer to:


 * Surname
 * Karen Karls, American politician
 * Ken Karls (born 1947), Chairman of the North Dakota Republican Party 2003–2007
 * Tommy Karls (born 1961), Swedish sprint and marathon canoeist


 * Other
 * Karls robber frog (Eleutherodactylus karlschmidti), a possibly extinct Puerto Rican frog species
 * Kong Karls Land, island group in the Svalbard archipelago, in the Arctic Ocean