Knucklehead

Knucklehead may refer to:
 * Harley-Davidson Knucklehead engine, introduced in 1936 as Model E, Harley-Davidson's first OHV engine
 * Knucklehead (2015 film), a film directed by Ben Bowman
 * Knucklehead (2010 film), a film produced by WWE Studios
 * Knucklehead (band), a Canadian punk rock group formed in Calgary, Canada in 1994
 * Knucklehead, B-side on the 1967 single "Soul Finger" by The Bar-Kays
 * Knucklehead, song by Grover Washington Jr., from the 1975 album Feels So Good
 * Knuckleheads, 2012 Canadian animated series
 * Knuckleheads Saloon, Kansas City, Missouri (where Karla Bonoff, Leon Redbone, and others have appeared)
 * Knuckle Heads, 1992 arcade game by Namco
 * Knuckleheads, 2008 platform game by Nitrome Limited
 * Knuckleheads Indoor Amusement Park, at Wisconsin Dells Parkway, Lake Delton, Wisconsin
 * Knucklehedz, member of hip hop collective Hit Squad

Characters

 * Knucklehead, the Mascot of the band Five Finger Death Punch
 * Knucklehead Smiff, ventriloquist dummy of Paul Winchell
 * Knucklehead, from The Pee-wee Herman Show stage show and the Pee-wee's Playhouse television series
 * Knucklehead, from the anime Battle Angel Alita
 * The Knuckleheads, nickname of The Three Stooges