L2E

L2E may refer to:


 * L2: Empuraan (film), a 2019 Malayalam-language action-thriller Indian film
 * Haplogroup L2e, a human mitochondrial haplogroup from West Africa
 * Category L2e, a European vehicle category
 * Postal Code L2E, a Canadian postal code for Niagara Falls, Ontario; see List of postal codes of Canada: L