LACA

LACA may refer to:


 * Los Angeles, California, the second most populous city in the US
 * lacA, a structural gene in the lac operon
 * Latin America and Central America, a designation used by American businesses doing business globally
 * Luxembourg Approach Controllers Association, the official representation of approach controllers in Luxembourg
 * Alexandre Lacazette (born 1991), nickname for the French footballer who plays for Arsenal.
 * Laca, south-eastern mountainside Barangay of Municipality of Jagna, Bohol, Philippines
 * Last archaean common ancestor, the last common ancestor of the archaea.