LCO

LCO may refer to:
 * Lac Courte Oreilles Band of Lake Superior Chippewa Indians
 * Lague Airport's IATA airport code, Republic of the Congo
 * Las Cachorras Orientales, a Japanese professional wrestling tag team
 * Las Campanas Observatory, an astronomical observatory in Chile
 * Launch Control Operator/Officer
 * Lawn Care Operator
 * League of Legends Circuit Oceania
 * Legislative Competence Order
 * Libraries Connect Ohio
 * lipochitin oligosaccharide / lipo-chitin oligosaccharide
 * Lithium cobalt oxide, a cathode material for lithium-ion batteries
 * Lithuanian Chamber Orchestra
 * Local Cable Operator, resell for multiple-system operator
 * London Chamber Orchestra
 * London Contemporary Orchestra