LFR

LFR can refer to:


 * Lead-cooled fast reactor, a type of nuclear reactor
 * LFR International, emergency medical service in Africa
 * Lay First Responder Model, a model of emergency assistance implemented by LFR International
 * Leavine Family Racing
 * Lincolnshire Fire and Rescue Service in England
 * Louisville Division of Fire, US
 * A US Navy hull classification symbol: Inshore fire support ship (LFR)
 * Leafs Fan Reaction, an internet series by Steve Dangle