LPE

LPE may refer to:


 * Lambda Pi Eta, a collegiate honor society
 * LAN Perú, an airline
 * Lapeer (Amtrak station), a train station
 * LimeWire Pirate Edition, file sharing software
 * Lingenfelter Performance Engineering, a car modifier
 * Liquid phase epitaxy, a semiconductor manufacturing process
 * Liquid phase exfoliation, a method of processing chemical solutions
 * Lone pair electrons, an atomic valence structure
 * Local privilege escalation, a type of software exploit
 * London Press Exchange, an advertising agency
 * Louisiana Purchase Exposition, 1940 World's Fair in St. Louis, MO
 * Lysophosphatidylethanolamine, a type of organic chemical
 * Longitude of the periapsis, a dimension of orbit
 * Lepki language, of Western New Guinea