LRN

LRN may refer to:


 * Laboratory Response Network, a collaborative effort of the U.S. Centers for Disease Control and Prevention and the Association of Public Health Laboratories
 * Land Rights News, the longest-running Aboriginal Australian newspaper, published by the Central and Northern Land Councils
 * Lateral reticular nucleus, a nucleus of the medulla oblongata involved with co-ordinating baroreceptor signals to control arterial blood pressure
 * Lead round nose, a type of bullet
 * Legislative route number, a designation for a highway defined by laws passed in a state legislature
 * Location Routing Number, a ten digit phone number used to route phone calls between two telephone exchanges
 * LORAN, a terrestrial radio navigation system originally known as LRN for Loomis Radio Navigation
 * LRN (company), an ethics compliance and education company
 * Luminous red nova, a stellar explosion thought to be caused by the merger of two stars