La Flesche

La Flesche may refer to:

People

 * Francis La Flesche (1857–1932), Native American ethnologist
 * Joseph LaFlesche (c. 1822–1888), head chief of the Omaha tribe
 * Marguerite La Flesche Diddock (1862–1945), Native American known for her work with the Office of Indian Affairs
 * Rosalie La Flesche Farley (1861–1900), Native American known for advocating for autonomy of the Omaha Tribe
 * Susan La Flesche Picotte (1865–1915), Native American medical doctor
 * Susette La Flesche (1854–1903), Native American writer

Other uses

 * Susan La Flesche Picotte House, house in Nebraska