Leucine 2,3-aminomutase

In enzymology, a leucine 2,3-aminomutase is an enzyme that catalyzes the chemical reaction


 * (2S)-alpha-leucine $$\rightleftharpoons$$ (3R)-beta-leucine

Hence, this enzyme is responsible for the conversion of -leucine to β-leucine.

This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring amino groups. The systematic name of this enzyme class is (2S)-alpha-leucine 2,3-aminomutase. This enzyme participates in valine, leucine and isoleucine degradation. It employs one cofactor, cobamide.