Lexington Historic District

Lexington Historic District may refer to:


 * Lexington Historic District (Lexington, Georgia), listed on the NRHP in Oglethorpe County, Georgia
 * Lexington Historic District (Lexington, Mississippi), NRHP-listed
 * Uptown Lexington Historic District, Lexington, North Carolina, listed on the NRHP in Davidson County, North Carolina
 * Lexington Historic District (Lexington, Virginia), listed on the NRHP in Lexington, Virginia
 * Several entries on the National Register of Historic Places listings in Fayette County, Kentucky