List of Alpha Sigma Alpha chapters

By 1912, all but four of the original chapters of Alpha Sigma Alpha had closed; most of its early chapters were placed at short-lived women's seminaries and the junior schools of the day. By the following year only the Alpha chapter remained. Rising to meet what was an existential challenge Alpha Sigma Alpha reorganized itself at a crucial fall 1914 convention to target growth into colleges with bona fide teachers programs, adding the practical aim of expansion by absorption of what was a series of local sororities. This strategy was successful.

Over several decades, teachers' colleges began to offer an expanded array of four-year degrees, while four-year schools were adding teacher programs. The AES was dissolved in 1947. By 1951 Alpha Sigma Alpha had once again shifted its focus, abandoning a self-imposed limit to serve only teachers colleges by opting to join the NPC as a full member and general sorority, and potentially serve all accredited colleges and universities.

Chapters
Following is a list of Alpha Sigma Alpha sorority chapters. Active chapters and colonies are noted in bold. Inactive chapters and institutions are noted in italics.