List of DePauw University fraternities and sororities

DePauw University, a small liberal arts college located in Greencastle, Indiana, bears the distinction of having an unusually high membership rate in Greek fraternities and sororities, rating consistently above 70% in recent years. For 2014, DePauw University was again ranked #1 in Greek Life by the Princeton Review. A position the school has held several times since over the past fifteen years including a stretch of seven consecutive years (2002-2008).

Following is a list of DePauw University fraternities and sororities.

Active fraternities

 * Alpha Tau Omega - ΑΤΩ, ATOs, founded at DePauw in 1924.
 * Beta Theta Pi - ΒΘΠ, Betas, founded at DePauw in 1845.
 * Delta Tau Delta - ΔΤΔ, Delts, founded at DePauw in 1882.
 * Delta Upsilon - ΔΥ, DUs, founded at DePauw in 1887.
 * Lambda Sigma Upsilon - ΛΣΥ, Elegua, founded at DePauw in 2012.
 * Phi Delta Theta - ΦΔΘ, Phi Delts, founded at DePauw in 1868.
 * Phi Gamma Delta - ΦΓΔ/FIJI, founded at DePauw in 1856. Currently the oldest active chapter of its fraternity.
 * Phi Kappa Psi - ΦΚΨ, Phi Psis, founded at DePauw in 1865.
 * Sigma Chi - ΣΧ, Sigs, founded at DePauw in 1859.
 * Sigma Nu - ΣΝ, Beta Beta Chapter, Sig Nus or SNus, founded at DePauw in 1890.
 * Sigma Alpha Epsilon - ΣΑΕ, SAEs, founded at DePauw in 1949. Suspended by its national organization during the 2016-2017 academic year. The fraternity became active again in 2019.

Active sororities

 * Alpha Chi Omega - ΑΧΏ -Alpha chapter, founded at DePauw in 1885.
 * Alpha Phi - ΑΦ -Gamma chapter, founded at DePauw in 1887
 * Delta Gamma - ΔΓ -Gamma Iota, founded at DePauw in 1949
 * Kappa Alpha Theta - ΚΑΘ -Alpha chapter, founded at DePauw in 1870, Theta is the first Greek-letter women's fraternity.
 * Kappa Kappa Gamma - ΚΚΓ -Iota chapter, founded at DePauw in 1875.
 * Pi Beta Phi - ΠΒΦ -Indiana Epsilon chapter, founded at DePauw in 1942.
 * Psi Lambda Xi - ΨΛΞ -A local sorority founded in March, 2007.
 * Alpha Kappa Alpha
 * Zeta Phi Beta
 * Sigma Lambda Gamma
 * Omega Phi Beta
 * Delta Sigma Theta

Inactive fraternities

 * Delta Kappa Epsilon
 * Lambda Chi Alpha
 * Delta Chi

Inactive sororities

 * Alpha Gamma Delta
 * Alpha Omicron Pi
 * Delta Delta Delta
 * Delta Zeta

Specialized Greek-letter organizations

 * Alpha Phi Omega - A coeducational volunteerism/service fraternity. Active.
 * Alpha Psi Omega - A coeducational honor society for students involved in the theatrical arts. Active.
 * Eta Sigma Phi - A coeducational honor society for students involved in the Classics. Active.
 * Chi Alpha Sigma - A coeducational honor society for athletes. Alpha chapter was founded at DePauw by former head football coach Nick Mourouzis.  Active.
 * Mu Phi Epsilon - A coeducational music fraternity. Active.
 * Phi Mu Alpha Sinfonia - A men's music fraternity. Inactive.
 * Sigma Delta Chi - Now known as the Society of Professional Journalists, the national organization was founded at DePauw in 1909. Active.