List of Indian Super League players

Since the Indian Super League's inaugural season in 2014, 37 players have accrued 100 or more appearances in the Indian Super League. The first player to reach the milestone was defender Mandar Rao Dessai, in representation of Goa and Mumbai City; his 100th match was Mumbai City's 3–0 win over East Bengal on 1 December 2020. Spanish defender Tiri is the first foreign player to make 100 appearances. Sunil Chhetri is the first player to make 100 appearance for a single club with Bengaluru and Edu Bedia is the first foreign player to do so with Goa.

Pritam Kotal is the first player to make 150 appearances in the Indian Super League.

List of players
Players are initially listed by number of appearances. If number of appearances are equal, the players are then listed chronologically by the year of first appearance. Current Indian Super League players and their current clubs are shown in bold.

Statistics are updated as of 29 December 2023.

Most appearances by club
Current Indian Super League clubs and players who hold the record for the club are shown in bold.

As of matches played on 29 December 2023.