List of Regis High School alumni

This list of alumni of Regis High School (New York City) includes graduates and students who did not graduate.


 * Vito Acconci (1940–2017) – performance artist and architect
 * Norberto Barba (born 1963) – television and film director
 * Adrian A. Basora (born 1938) – diplomat; U.S. Ambassador to the Czech Republic (1993–95)
 * Michael Bérubé (born 1961) – Paterno Family Professor in Literature, Pennsylvania State University
 * Adrian P. Burke (1904–2000) – American lawyer, appellate judge (New York Court of Appeals), and politician.
 * Kevin Burke – chairman, president, and CEO, Consolidated Edison
 * Frank Joseph Caggiano (born 1959) – Bishop of Bridgeport (Connecticut)
 * Thomas Cahill (born 1940) – scholar and writer; author, Hinges of History series
 * Timothy Chorba (born 1946) – diplomat; U.S. Ambassador to Singapore (1994–97)
 * Bill Condon (born 1955) – director and Academy Award-winning screenwriter
 * Edward Conlon (born 1965) – New York Police Department police officer; bestselling author
 * John M. Corridan (1911–1984) – Jesuit priest; organized crime fighter on the New York City waterfront (inspiration for Fr. Barry in On the Waterfront)
 * Declan Cronin, major league baseball player
 * John D'Agostino – exchange markets expert; subject of Ben Mezrich's Rigged
 * John D'Emilio (born 1948) – academic, historian, and activist
 * Lou DiBella (born 1960) – boxing promoter
 * Kieran Donohue – college basketball coach
 * John Donvan (born 1955) – journalist; ABC News Nightline correspondent
 * Anthony Fauci (born 1940) – infectious diseases physician, HIV/AIDS researcher; head of the National Institute of Allergy and Infectious Diseases
 * John D. Feeley (born 1961) – diplomat, U.S. Ambassador to Panama (2016–18)
 * Chuck Feeney (1931–2023) – businessman and philanthropist; did not graduate (attended for 1.5 years)
 * Patrick Fitzgerald (born 1960) – U.S. Attorney; Central Intelligence Agency Leak Investigation Special Prosecutor
 * Steve Fuller – founder of social epistemology; professor at the University of Warwick, United Kingdom
 * Greg Giraldo (1965–2010) – comedian and television personality
 * Robert Giroux (1914–2008) – publisher, Harcourt, Brace & Company and Farrar, Straus and Giroux
 * Frederick Gluck (born 1935) – managing director, McKinsey & Company (1988–1994)
 * Pete Hamill (1935–2020) – writer and columnist; did not graduate (attended until age 16); awarded honorary diploma in 2010
 * Charles Harbutt (1935–2015) – photographer
 * Donald J. Harrington (born 1945) – former president, St. John's University; former president, Niagara University
 * Andrew P. Harris (born 1957) – Member of Congress
 * Timothy S. Healy (1923–1992) – president, Georgetown University and the New York Public Library
 * Rich Hickey – creator of the programming language Clojure
 * Robert Hilferty – filmmaker, journalist, and HIV/AIDS activist
 * Steve Hirdt – executive vice president, Elias Sports Bureau
 * Colin Jost (born 1982), head writer and Weekend Update co-anchor, Saturday Night Live; stand-up comedian
 * Brian P. Kavanagh (born 1967) – New York State Senator
 * John F. Keenan (born 1929) – judge, U.S. District Court for the Southern District of New York
 * Thomas C. Kelly (1931–2011) – archbishop, Roman Catholic Archdiocese of Louisville (Kentucky)
 * Tom Kelly (1924–2008) – former Boston Celtics basketball player
 * Phil Klay (born 1983) – winner, National Book Award for fiction in 2014 for Redeployment
 * John Koeltl (born 1945) – judge, U.S. District Court for the Southern District of New York
 * David Lat (born 1975) – founder and managing editor, Above the Law legal blog
 * John Leo (born 1935) – author; former columnist, U.S. News & World Report
 * Thomas Lippman (born 1939) – journalist and author; Middle East specialist
 * Chris Lowney (born 1958) – Christian author and speaker
 * Gerard E. Lynch (born 1951) – circuit judge, U.S. Court of Appeals for the Second Circuit
 * John Maguire (1904–1989) – bishop, Roman Catholic Archdiocese of New York
 * Eugene T. Maleska (1916–1993) – editor, New York Times crossword puzzle
 * Robert Marasco (1936–1998) – playwright
 * Mark Mazzetti (born 1974) – Pulitzer Prize-winning New York Times writer
 * Ken McCarthy (born 1959) – Internet commercialization pioneer, educator, activist
 * Mac McGarry (1926–2013) – host, the Washington, D.C., and Charlottesville, Virginia, versions of the television student quiz show It's Academic
 * John McGiver (1913–1975) – film and television character actor
 * Lawrence M. McKenna (1933–2023) – judge, U.S. District Court for the Southern District of New York
 * Joseph M. McShane (born 1949) – president, Fordham University (2003–22)
 * Ronald J. Mellor (born 1940) – scholar, ancient history and religion
 * Arthur Minson Jr. (born 1970) – Co-CEO, WeWork
 * Alexander J. Motyl (born 1953) – political scientist, Rutgers University
 * Thomas Francis Murphy (1906–1995) – government official in the perjury trials of Alger Hiss
 * John Nonna (born 1948) – 1972 Summer Olympics fencer
 * Lucio Noto (born 1938) – petroleum executive
 * Frank S. Nugent (1908–1965) – New York Times film critic; screenwriter (The Quiet Man (1952), The Searchers (1956))
 * Edward J. O'Donnell (1931–2009) – bishop, Roman Catholic Diocese of Lafayette (Louisiana)
 * Joseph A. O'Hare (1931–2020) – president, Fordham University; chairman, New York City Campaign Finance Board; editor, America magazine
 * John O'Keefe (born 1939) – Nobel laureate in Physiology or Medicine, 2014
 * Francis Edward Peters (born 1927) – scholar of Middle East religion, New York University
 * Patrick Quinlan – political activist and author
 * Gerard Reedy (1939–2016) – president, College of the Holy Cross
 * Ken Rosato – journalist; WABC-TV Eyewitness News anchor
 * Sandro Santagata (born 1971) – clinical pathologist
 * Lucy Sante (born 1954) – writer and critic; graduated as Luc Sante
 * Jon Sciambi (born 1970) – sportscaster, ESPN
 * Jim Sciutto (born 1970) – journalist; Chief National Security Correspondent, CNN
 * Joe Sheehan – founding member, BaseballProspectus.com; sports writer
 * William F. Smith (1901–1950) – lawyer; member, New York State Assembly
 * Roger Stigliano (born 1954) – film director and screenwriter; winner, Teddy Award at Berlin Film Festival (1989)
 * Brian Thomsen (1959–2008) – science fiction writer
 * Robert Tomasulo (1934–2008) – computer scientist; devised the Tomasulo algorithm named for him
 * Pablo S. Torre (born 1985) – sportswriter, ESPN.com and ESPN The Magazine; panelist, ESPN shows, including Around the Horn
 * Mike Walczewski (born 1956) – public address announcer, New York Knicks and Madison Square Garden
 * William Braucher Wood (born 1950) – diplomat; U.S. Ambassador to Colombia (2003–07) and Afghanistan (2007–09)