List of Superfund sites in Missouri

This is a list of Superfund sites in Missouri designated under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) environmental law. The CERCLA federal law of 1980 authorized the United States Environmental Protection Agency (EPA) to create a list of polluted locations requiring a long-term response to clean up hazardous material contaminations. These locations are known as Superfund sites, and are placed on the National Priorities List (NPL).

The NPL guides the EPA in "determining which sites warrant further investigation" for environmental remediation. As of May 1, 2010, there were thirty Superfund sites on the National Priorities List in Missouri. One more site has been proposed for entry on the list and five others have been cleaned up and removed from it.