List of UK R&B Singles Chart number ones of 2001

The UK R&B Chart is a weekly chart that ranks the 40 biggest-selling singles and albums that are classified in the R&B genre in the United Kingdom. The chart is compiled by the Official Charts Company, and is based on physical formats. This is a list of the UK's biggest R&B hits of 2001 but erroneously includes tracks from other genres, for example Eminem (Hip hop), Shaggy (Dancehall) and Daniel Bedingfield (UK Garage).