List of University of Southern Mississippi fraternities and sororities

The University of Southern Mississippi, informally known as "Southern Miss", is home to more than thirty national fraternity and sorority chapters. These chapters are under the authority of various groups. The North American Interfraternity Conference and National Panhellenic Conference members are under the authority of Greek Life. Non-affiliated fraternities and sororities such as Beta Upsilon Chi and Sigma Alpha Iota fall under the Department of Student Activities.

Following is a list of University of Southern Mississippi fraternities and sororities, organized by national umbrella organizations.

National Pan-Hellenic Council
The following organizations are members of the National Pan-Hellenic Council
 * Alpha Kappa Alpha
 * Alpha Phi Alpha
 * Delta Sigma Theta
 * Iota Phi Theta
 * Kappa Alpha Psi
 * Omega Psi Phi
 * Phi Beta Sigma
 * Sigma Gamma Rho
 * Zeta Phi Beta

National Panhellenic Conference
The following sororities are members of the National Panhellenic Conference.
 * Alpha Chi Omega
 * Alpha Delta Pi
 * Alpha Sigma Alpha (inactive)
 * Chi Omega
 * Delta Delta Delta
 * Delta Gamma
 * Delta Zeta (inactive)
 * Kappa Alpha Theta (inactive)
 * Kappa Delta
 * Pi Beta Phi
 * Phi Mu
 * Sigma Sigma Sigma (inactive)

North American Interfraternity Conference
The following fraternities are members of the North American Interfraternity Conference.
 * Acacia Fraternity (inactive)
 * Alpha Tau Omega
 * Delta Tau Delta
 * Kappa Alpha Order (inactive)
 * Kappa Sigma
 * Pi Kappa Alpha
 * Pi Kappa Phi
 * Phi Kappa Tau
 * Sigma Alpha Epsilon
 * Sigma Chi (inactive)
 * Sigma Nu
 * Sigma Phi Epsilon
 * Tau Kappa Epsilon (inactive)

Other organizations

 * Beta Upsilon Chi, Christian fraternity
 * Mu Phi Epsilon, professional music fraternity
 * Phi Mu Alpha Sinfonia, social music fraternity
 * Sigma Alpha Iota, professional music sorority