List of adverse effects of aripiprazole

The rates of adverse effects of aripiprazole are:

Very common (>10% incidence)

 * Weight gain
 * Headache
 * Agitation
 * Insomnia
 * Anxiety
 * Nausea & vomiting
 * Akathisia — a sense of unease and restlessness that presents itself with anxiety
 * Lightheadedness
 * Constipation
 * Emotional instability
 * Euphoria or Dysphoria

Common (1–10% incidence)

 * Dizziness
 * Dyspepsia — indigestion
 * Somnolence — which is usually mild and transient and less severe than that seen with most antipsychotics.
 * Fatigue
 * Restlessness
 * Dry mouth
 * Extrapyramidal side effects (e.g. dystonia, parkinsonism, tremor, myoclonic jerks, etc.)
 * Orthostatic hypotension
 * Musculoskeletal stiffness
 * Abdominal discomfort
 * Blurred vision
 * Cough
 * Pain
 * Myalgia
 * Rash
 * Rhinitis

Uncommon (0.1–1% incidence)

 * Leukopenia
 * Thrombocytopenia
 * Bradycardia (low heart rate)
 * Palpitations
 * Orthostatic hypotension
 * Dry eye
 * Photophobia
 * Diplopia
 * Eyelid oedema
 * Photopsia
 * Diarrhoea
 * Gastritis
 * Pathological gambling
 * Dysphagia
 * Gastroesophageal reflux disease
 * Swollen tongue
 * Oesophagitis
 * Hypoaesthesia oral
 * Face oedema
 * Gait disturbance
 * Chills
 * Discomfort
 * Feeling abnormal
 * Mobility decreased
 * Self-mutilation
 * Heart rate increased
 * Blood glucose increased
 * Pyrexia
 * Blood prolactin increased
 * Blood urea increased
 * Electrocardiogram QT prolonged
 * Blood bilirubin increased
 * Hepatic enzyme increased
 * Increased appetite
 * Nocturia
 * Polyuria
 * Pollakiuria
 * Incontinence
 * Urinary retention
 * Sexual dysfunction
 * Amenorrhoea
 * Pruritus
 * Photosensitivity reaction
 * Urticaria

Rare (<0.1%)

 * Neuroleptic malignant syndrome (Combination of fever, muscle stiffness, faster breathing, sweating, reduced consciousness, and sudden change in blood pressure and heart rate)
 * Neutropenia
 * Suicidal ideation and behavior
 * Depression
 * Painful and/or sustained erection (Priapism)
 * Seizures
 * Rhabdomyolysis
 * Agranulocytosis
 * Cardiopulmonary failure
 * Myocardial infarction (heart attack)
 * Atrial flutter
 * Supraventricular tachycardia
 * Ventricular tachycardia
 * Atrioventricular block
 * Extrasystoles
 * Sinus tachycardia
 * Atrial fibrillation
 * Angina pectoris
 * Myocardial ischaemia
 * Pancreatitis
 * Diabetic ketoacidosis
 * Prolonged QT interval (less common than with most other atypical antipsychotic drugs)
 * Speech disorder
 * Electrolyte abnormalities including hyponatraemia, hypokalaemia, hypocalcaemia, etc.
 * Hypertension
 * Dysphagia
 * Oropharyngeal spasm
 * Laryngospasm
 * Hepatitis
 * Jaundice
 * Hypersalivation
 * Chest pain
 * Urinary retention or incontinence
 * Alopecia (hair loss)
 * Photosensitivity reaction
 * Rash
 * Xerostomia (when given by injection)
 * Tardive dyskinesia (As with all antipsychotic medication, patients using aripiprazole may develop the permanent neurological disorder tardive dyskinesia.)
 * Stroke
 * Transient Ischaemic Attack
 * Increased body temperature
 * Angioedema
 * Cardiorespiratory arrest
 * Cardiorespiratory failure

Sudden unexplained death has been reported, however the frequency is unknown.

Common in children

 * Feeling sleepy
 * Headache
 * Vomiting
 * Fatigue
 * Increased appetite
 * Insomnia
 * Nausea
 * Stuffy nose
 * Weight gain
 * Uncontrolled movement such as restlessness, tremor muscle stiffness